Having just had a cholesterol test done which shows that I have good LDL that is at a level that can reverse plaque in the circulatory system I renewed my interest in an article May 2013 I read in the National Geographic that stated "This baby will live to be 120"
Much of the study & research is now aimed at finding health promoting genes which replaces the out dated ideas of finding disease causing genes.
One of the genetic finds is that people who live into their 90`s and beyond tend to possess a particular version, or allele, of a gene important to taste & digestion.
This allele gives people a taste for bitter foods like broccoli and field greens which are typically rich in compounds known as polyphenols that promote cellular health and also allows cells in the intestine to extract nutrients more efficiently from food as it is being digested.
Researcher Passarino has also found in his centenarians a revved-up version of a gene for what is called an uncoupling protein. The protein plays a central role in metabolism - the way a person consumes energy and regulates body heat- which in turn affects the rate of ageing. Passsarino has dissected five to six pathways that most influence longevity. Most of them involve the response to stress, the metabolism of nutrients, or metabolism in general.
There are genetic anomalies that have been found to protect against age related diseases such as diabetes & cancer.
The research into genes is beginning to show also that previously thought incurable diseases are now more survivable due to some of the advances in science & medicine.
Although some of the centenarians that were interviewed mentioned frugal diet, little meat, a little bit of everything this hasn't yet been supported by science and whilst being overweight is now known to be a high risk factor for premature death the evidence for a low calorie intake is conflicting. It is likely that genes account for about 25% of influence in longevity and a good proportion down to environment and a balanced lifestyle.
There are people such as Irving Kahn 106,who still works five hours a day as the Chairman of the New York City Investment advisory and brokerage firm that bears the family name. He has been called the world`s oldest active investment professional.
Giuseppe Romeo 101,makes his own pasta and knows how to massage away his own aches and pains skills he perfected as a prisoner of war after he was captured by the British during World War II.
The centenarian also enjoys whittling.
Full article please see May 2013 National Geographic